表达区间及表达系统(Source)
Recombinant Cynomolgus CD79A Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Leu33-Arg142 [Accession | XP_045235481.1].
分子量大小(Molecular Weight)
The protein has a predicted MW of 13.94 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
纯度(Purity)
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
内毒素(Endotoxin)
Less than 1 EU per μg by the LAL method.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
重构方法(Reconstitution)
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
存储(Storage)
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
产品数据
Cynomolgus CD79A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
The purity of Cynomolgus CD79A is greater than 95% as determined by SEC-HPLC. |
CD79 is a heterodimeric molecule comprising two polypeptide chains, B29 (CD79b) and mb-1 (CD79a). It is physically linked in the surface of B cells to membrane immunoglobulin, forming the B cell antigen receptor complex. Expression of the mb-1 (CD79a) chain has been studied in leukaemias and shown to be present in most B lineage acute lymphoblastic leukaemias (ALL).
分子别名(Synonyms)
Ig-alpha; CD79a; IGA; MB1
文献(References)
Astsaturov IA, Matutes E, Morilla R, Seon BK, Mason DY, Farahat N, Catovsky D. Differential expression of B29 (CD79b) and mb-1 (CD79a) proteins in acute lymphoblastic leukaemia. Leukemia. 1996 May;10(5):769-73. PMID: 8656670.

